Cologne Spring Meeting 2008

Cologne Spring Meeting 2008

Mouse Models Of Human Diseases

March 12 - 14, 2008

Organizers: Manolis Pasparakis, Jens Brüning, Ursula Lichtenberg, Martin Hafner
Institute for Genetics, University of Cologne

The aim of the Cologne Spring Meeting 2008 is to bring together scientists that develop and use genetic mouse models to understand the mechanisms causing human disease. The meeting will cover the latest developments in mouse genetic engineering and in the application of mouse models to study the mechanisms of human diseases including inflammatory, degenerative and metabolic diseases and cancer.

Venue:

Institute of Physics
University of Cologne
Zülpicher Straße 77
50937 Cologne

Download of Poster: pdf

Download of Program: pdf

Program:

Wednesday, March 12, 2008
14:00 - 14:10 Opening remarks  
14:10 - 14:50 Klaus Rajewsky, Harvard University, Boston MicroRNA-based control mechanisms and pathologies in the immune system
14:50 -15:30 Jost Seibler, Artemis Pharmaceuticals, Cologne Reversible RNAi-mediated Knockdown for Gene Function Analysis in Mice
15:30 - 16:10 Konrad Hochedlinger, Massachusetts General Hospital Cancer Center, Boston Reprogramming of somatic cells into embryonic stem cells
16:10 - 16:40 Coffee Break  
16:40 - 17:20 Denis Duboule, University of Geneva, Geneva & EPFL SV ISREC, Lausanne Engineering chromosomes in vivo to study mammalian development and diseases
17:20 - 18:00 Allan Bradley, Wellcome Trust Sanger Institute, Cambridge, UK The Quest for Homozygosity
     
Thursday, March 13, 2008
9:00 - 9:40 Elena Rugarli, National Neurological Institute, Milan The mitochondrial-AAA protease: a culprit in neurodegeneration
9:40 - 10:20 Lenhard Rudolph, University of Ulm, Ulm Cell intrinsic checkpoints and environmental alterations limiting stem cell function in response to telomere dysfunction
10:20 - 10:50 Coffee Break  
10:50 - 11:30 Björn Schumacher, Erasmus Medical Center, Rotterdam DNA damage in aging and cancer
11:30 - 12:10 Jos Jonkers, The Netherlands Cancer Institute, Amsterdam Conditional Mouse Models of Breast Cancer
12:10 - 14:00 Lunch Break  
14:00 - 14:40 Adriano Aguzzi, Institute of Neuropathology, Zürich Biology of Mammalian Prions
14:40 - 15:20 Mark Sleeman, Regeneron Pharmaceuticals, New York Specific Deletion of Glucagon in Mice (GCG-/-) Highlights the Dominant Role this Peptide Plays in Bodyweight and Glucose Homeostasis
15:20 - 16:00 Jens Brüning, Institute for Genetics, Cologne Functional characterization of neurocircuits in control of energy homeostasis
16:00 - 16:30 Coffee Break  
16:30 - 17:10 Elaine Fuchs, Rockefeller University, New York Skin Stem Cells and Their Lineages
17:10 - 17:50 Fiona Watt, Cambridge Research Institute, Cambridge UK Stem cells and lineage selection in mammalian epidermis
17:50 - 18:30 Carien Niessen, Center for Molecular Medicine, Cologne Regulatory pathways determining epidermal morphogenesis and barrier function
     
Friday, March 14, 2008
9:00 - 9:40 Jürg Tschopp, University of Lausanne, Lausanne From Inflammasomes to fever: How basic research explains diseases
9:40 - 10:20 George Kollias, B.S.R.C. "Alexander Fleming", Athens Mechanisms of TNF Function in Chronic Inflammation and Autoimmunity
10:20 - 10:50 Coffee Break  
10:50 -11:30 Markus Moser, Max Planck Institute of Biochemistry, Martinsried Genetic analysis of integrin activation in mice
11:30 - 12:10 Fiona Powrie, University of Oxford, Oxford Intestinal homeostasis: a balancing act between effector and regulatory pathways
12:10 - 14:00 Lunch Break  
14:00 - 14:40 Manolis Pasparakis, Institute for Genetics, Cologne IKK/NF-kappaB signalling in inflammation and cancer
14:40 - 15:20 Josef Penninger, Institute of Molecular Biotechnology, Vienna Molecular control of acute lung failure
15:20 - 15:30 Closing of the meeting 
End of the Meeting

Sponsors

The organizers appreciate financial support for this meeting by the following institutions:

General Information:

The meeting is open and no registration or attendance fee is required. Accommodation may be arranged through the Cologne Tourist Office, Unter Fettenhennen 19, D-50667 Köln, Germany.

Important information for those who plan to travel by car: Since January 1st 2008, a Low Emission Zone has been introduced in Cologne. The University of Cologne is outside of this zone but most hotels are situated inside this zone. Please find more information here.

Contact:

spring-meeting@uni-koeln.de

last update: March 11, 2008