Lab of Thomas Klein
 
Thomas Klein
 
Genetics Düsseldorf
Genetics Cologne
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Kaspar M, Schneider M, Chia W, Klein T.
Klumpfuss is involved in the determination of sensory organ precursors in Drosophila.
Dev. Biol. 2008 (in press)

Geffers I., Serth K., Chapman G., Jaekel R., Schuster-Gossler K., Cordes R., Sparrow D.B.,
Kremmer E., Dunwoodie S.L., Klein T., and Gossler A.
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
Journal of Cell Biology 2007 Jul; 178, 465-476

Klein T.
Immunolabelling of imaginal discs.
In: Methods in Molecular Biology, Volume: Drosophila, ed. Christian Dahmann
Humana Press 2006

Jaekel R. and Klein T.
The Drosophila Notch inhibitor and tumour suppressor gene lethal (2) giant discs
encodes a conserved regulator of endosomal trafficking.

Dev. Cell 2006 Nov; 11, 655-669

Kaspar M. and Klein T.
Functional analysis of murine CBF1 during Drosophila development.
Dev. Dyn. 2006 Apr; 9, 18-27

Kölzer S. and Klein T.
Regulation of expression of Vg and establishment of the dorsoventral compartment boundary
in the wing imaginal disc by Suppressor of Hairless.

Dev. Biol. 2006 Jan; 289, 77-90.

Klein T.
Notch-pathway.
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.
Springer-Verlag

Kölzer S, Fuss B., Hoch M. and Klein T.
The homeobox transcription factor encoded by the defective ventriculus (dve) gene is required
for pattern formation along the proximo-distal axis, cell proliferation and formation of veins
in the Drosophila wing.

Development 2003 Sep; 130, 4135-4147.

Klein T.
The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch
to the dorsoventral boundary during Drosophila wing development.

Dev. Biol. 2003 Mar; 255(2):313-33.

Koelzer S, Klein T.
A Notch-independent function of Suppressor of Hairless during the development of the bristle
sensory organ precursor cell of Drosophila.

Development 2003 May; 130(9):1973-88.

Klein T.
Kuzbanian is required cell autonomously during Notch signalling in the Drosophila wing.
Dev. Genes. Evol. 2002 Jun;212(5):251-5. Epub 2002 Apr 20.

Klein T.
Wing disc development in the fly: The early stages.
Curr. Opin. Gen. Dev. 2001 Aug; 11, 470-475

Klein T., Seugnet L., Haenlin M., Martinez Arias A.
Two different activities of Suppressor of Hairless during wing development in Drosophila.
Development 2000 Aug; 127(16):3553-66.

Lawrence N., Klein T., Brennan K., Martinez Arias A.
Structural requirements for notch signalling with delta and serrate during the development and
patterning of the wing disc of Drosophila.

Development 2000 Jul; 127(14):3185-95.

Brennan K., Klein T., Wilder E., Arias AM.
Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila.
Dev. Biol. 1999 Dec 1; 216(1):210-29.

Bishop S.A., Klein T., Arias AM, Couso J.P.
Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch.
Development 1999 Jul; 126(13):2993-3003.

Klein T., Arias AM.
The vestigial gene product provides a molecular context for the interpretation of signals during
the development of the wing in Drosophila.

Development 1999 Feb; 126(5):913-25.

Klein, T., Couso J.P. and Martinez-Arias A.
Wing development and specification of dorsal cell fates in the absence of apterous in Drosophila.
Current Biology 1998 Mar; 8, 417-420

Klein T., Arias AM.
Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development.
Development 1998 Aug;125(15):2951-62.

Klein T. and Arias AM.
Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal
and distal pattern elements of the wing in Drosophila.

Dev. Biol. 1998 Feb 15; 194(2):196-212.

Klein T. and Campos-Ortega J.A.
klumpfuss. a Drosophila gene encoding a member of the EGR family of transcription factors,
is involved in bristle and leg development.

Development 1997 Aug; 124, 3123-3134

Yang X., Bahri, S., Klein T. and Chia W.
klumpfuss, a putative EGR-1 family transcription regulator, acts to differentiate between the identities
of two secondary progenitor cells within one neuroblast lineage.

Genes. Dev. 1997 Jun; 11, 1396-1408

Klein T., Brennan K. and Arias AM.
An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila.
Dev. Biol. 1997 Sep; 189(1):123-34.

Hart K, Klein T. and Wilcox M.
A minute encoding a ribosomal protein enhances wing morphogenesis mutants.
Mech. Dev. 1993 Oct; 43, 101-110

Klein T. and Campos-Ortega J. A.
Second-site modifier of the Delta wing phenotype in Drosophila melanogaster.
Roux's Arch. Dev. Biol. 1992 Dec; 202, 49-60

Klein T. and Briegleb W.
Bau, Funktion und Leistung des Vestibularsystems: Vergleich von Wasser-und Landvertebraten
Institut für Flugmedizin, DLR 1988; IB 316-88-03